Vitamin C A water-soluble antioxidant and ascorbic acid Found in: citrus and other fruits, berries, and vegetables Benefits: protects against free radicals, boosts collagen Product: Performance Collagen DHH-B A compound within the bark of Magnolia trees Found in: Magnolia officinalis and grandiflora Benefits: anxiety and stress relief, sleep enhancement Product: DHH-B Apigen A bioflavonoid found in many plants Found in: fruits, vegetables, parsley, celery Benefits: heart health, eased anxiety and depression, improved mood Product: Apigen Nobiletin A flavanoid called polymenthoxylated flavones (PMF) Found in: tangerines, oranges, and lemons Benefits: anti-inflammatory, metabolic health, anti-cancer properties Product: Sytrinol LNA Tributyrin A naturally occurring triglyceride Found in: butter and other animal fats Benefits: supports immune health, improved gastrointestinal health Product: nuButyrate AKG A precursor to Glutamine and glutamate Found in: Poultry, red meats, fish and shrimp Benefits: supports muscle health, bone mass, fertility Product: AKG+ Resveratrol A natural polyphenol found in various plants Found in: red wine, peanuts, grapes, berries Benefits: antioxidant, supports metabolism Product: Leusynergy

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This distinction is particularly useful in experimental designs where separation of adipose-specific signaling from systemic endocrine effects is required
Synthetic hormones, specifically progestins, by an oral route led to the creation of metabolites in the liver which caused an increase in the incidence of breast and uterine cancers